需要我们反思的“肠型分析”

Title：
Rethinking "enterotypes"

DOI：
10.1016/j.chom.2014.09.013

Abstract：
Classification of the human gut microbiome into distinct types, or "enterotypes," provides an attractive framework for understanding microbial variation in health and disease. However, as discussed here, several different methods of collapsing enterotype variation into a few discrete clusters suggest that enterotype distribution is continuous and can vary widely within an individual.

All Authors：
Dan Knights,Tonya L Ward,Christopher E McKinlay,Hannah Miller,Antonio Gonzalez,Rob Knight,Daniel Mcdonald

First Authors：
Dan Knights

Correspondence：
Rob Knight

内容要点：

   肠型这个概念的提出，提供了一个可靠的框架让人们更多理解健康和疾病人群的微生物多样性。但自从2011年第一次提出肠型后，不断有新的科学家尝试用新的数据方法来研究多样性，越来越多的方法认为，多样性不是只有三种，而是连续的。