抗性淀粉对肠道菌群的调节作用
Title：
Resistant Starch Regulates Gut Microbiota: Structure, Biochemistry and Cell Signalling
Abstract：
Starch is one of the most popular nutritional sources for both human and animals. Due to the variation of its nutritional traits and biochemical specificities, starch has been classified into rapidly digestible, slowly digestible and resistant starch. Resistant starch has its own unique chemical structure, and various forms of resistant starch are commercially available. It has been found being a multiple-functional regulator for treating metabolic dysfunction. Different functions of resistant starch such as modulation of the gut microbiota, gut peptides, circulating growth factors, circulating inflammatory mediators have been characterized by animal studies and clinical trials. In this mini-review, recent remarkable progress in resistant starch on gut microbiota, particularly the effect of structure, biochemistry and cell signaling on nutrition has been summarized, with highlights on its regulatory effect on gut microbiota.
All Authors：
Xiaoping Yang,Kwame Oteng Darko,Yanjun Huang,Caimei He,Huansheng Yang,Shanping He,Jianzhong Li,Jian Li,Berthold Hocher,Yulong Yin
First Authors：
Xiaoping Yang
Correspondence：
Xiaoping Yang,Yulong Yin
内容要点：
动物实验及临床试验表明，抗性淀粉（RS）具有调节肠道菌群、肠道肽、循环生长因子，循环炎症介质等多种功能。本文综述RS最新研究进展，特别是RS的结构、生化性质及细胞信号对营养的影响，突出了RS对肠道菌群的调节效应。膳食RS提高肠道菌群中布氏瘤胃球菌数量，增加短链脂肪酸的浓度、改善菌群的代谢、增加胰岛素敏感性。 需加速研究RS的实际应用，如预防人类代谢性疾病、生产高品质肉制品等。